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Webinars
Articles

       The Reading Room

Articles & Research

Sep 23 2026
INDUSTRY NEWS
Advanced NSCLCTargeted Therapies

Zidesamtinib produced responses in 94% of ROS1 TKI-naive patients in ARROS-1

Sep 18 2026
INDUSTRY NEWS
Advanced NSCLCTargeted Therapies

Sevabertinib approved in the US for untreated HER2-mutant NSCLC

Sep 17 2026
RESEARCH
Advanced NSCLCTargeted Therapies

Grade 3 adverse events on the FLAURA2 combination fell from 43% during induction to 14% on osimertinib alone

D. Planchard
Sep 16 2026
INDUSTRY NEWS
Advanced NSCLCImmunotherapies

First-line trastuzumab deruxtecan extended median PFS to 14.3 months in HER2-mutant NSCLC

Sep 15 2026
CONGRESS
Advanced NSCLCImmunotherapies

HARMONi-2: ivonescimab extends overall survival over pembrolizumab in China

Sep 15 2026
CONGRESS
Advanced NSCLCBiomarkersResectable NSCLC

WCLC 2026, day 4: tumour budding, BRAF class II and III, brain radiotherapy timing, and mobile CT screening

Sep 14 2026
CONGRESS
Advanced NSCLCResectable NSCLCADCs

WCLC 2026, day 3: EGFR exon 20, ROS1 and HER2 in advanced NSCLC, and 79% alive at eight years after surgery

Sep 14 2026
CONGRESS
Advanced NSCLCADCs

DESTINY-Lung04: first-line T-DXd adds six months of PFS, no interim survival gain

Sep 14 2026
CONGRESS
Advanced NSCLCTargeted Therapies

PAPILLON final OS: 34.3 vs 27.9 months, HR 0.87 not significant after 76% crossover

Sep 14 2026
CONGRESS
Advanced NSCLCTargeted Therapies

REZILIENT 3: zipalertinib plus chemotherapy adds six months of first-line PFS

Sep 14 2026
CONGRESS
Advanced NSCLCTargeted Therapies

ARROS-1: first-line zidesamtinib responds in over 90% of ROS1-positive NSCLC

Giannis Mountzios
Sep 13 2026
CONGRESS
Advanced NSCLCADCsImmunotherapies

EVOKE-03: sacituzumab govitecan plus pembrolizumab misses both primary endpoints

G. Mountzios
Sep 13 2026
CONGRESS
Advanced NSCLCSCLCADCs

WCLC 2026, day 2: MRI surveillance without prophylactic cranial irradiation, and two relapse trials at 13.3 and 18.5 months

Sep 12 2026
CONGRESS
Advanced NSCLCResectable NSCLCSCLC

WCLC 2026, day 1: extended-interval and subcutaneous dosing in SCLC, and a 70% early response

Sep 09 2026
INDUSTRY NEWS
Advanced NSCLCImmunotherapies

HARMONi primary analysis reports 6.8 against 4.4 months PFS for ivonescimab plus chemotherapy after EGFR TKI progression

Sep 08 2026
RESEARCH
Advanced NSCLCImmunotherapies

Pleural metastases carried worse two-year survival than contralateral lung metastases in stage M1a NSCLC

L. Hendriks
Sep 04 2026
RESEARCH
Advanced NSCLCTargeted Therapies

An EGFR-SHC1 fusion resists EGFR inhibitors through its non-kinase partner

X. Le
Sep 03 2026
INDUSTRY NEWS
Advanced NSCLCImmunotherapies

Akeso reports an OS benefit for ivonescimab over pembrolizumab in PD-L1-positive NSCLC

Sep 02 2026
RESEARCH
Advanced NSCLCImmunotherapies

AI-HOPE registry recruits 920 patients to build machine-learning models for metastatic NSCLC outcomes

R. FerraraL. Hendriks
Aug 29 2026
RESEARCH
Advanced NSCLCADCs

International panel sets 55 consensus recommendations for managing Dato-DXd side effects in NSCLC

S. Saw

       The Reading Room

Articles & Research

Sep 23 2026
INDUSTRY NEWS
Advanced NSCLCTargeted Therapies

Zidesamtinib produced responses in 94% of ROS1 TKI-naive patients in ARROS-1

Sep 18 2026
INDUSTRY NEWS
Advanced NSCLCTargeted Therapies

Sevabertinib approved in the US for untreated HER2-mutant NSCLC

Sep 17 2026
RESEARCH
Advanced NSCLCTargeted Therapies

Grade 3 adverse events on the FLAURA2 combination fell from 43% during induction to 14% on osimertinib alone

D. Planchard
Sep 16 2026
INDUSTRY NEWS
Advanced NSCLCImmunotherapies

First-line trastuzumab deruxtecan extended median PFS to 14.3 months in HER2-mutant NSCLC

Sep 15 2026
CONGRESS
Advanced NSCLCImmunotherapies

HARMONi-2: ivonescimab extends overall survival over pembrolizumab in China

Sep 15 2026
CONGRESS
Advanced NSCLCBiomarkersResectable NSCLC

WCLC 2026, day 4: tumour budding, BRAF class II and III, brain radiotherapy timing, and mobile CT screening

Sep 14 2026
CONGRESS
Advanced NSCLCResectable NSCLCADCs

WCLC 2026, day 3: EGFR exon 20, ROS1 and HER2 in advanced NSCLC, and 79% alive at eight years after surgery

Sep 14 2026
CONGRESS
Advanced NSCLCADCs

DESTINY-Lung04: first-line T-DXd adds six months of PFS, no interim survival gain

Sep 14 2026
CONGRESS
Advanced NSCLCTargeted Therapies

PAPILLON final OS: 34.3 vs 27.9 months, HR 0.87 not significant after 76% crossover

Sep 14 2026
CONGRESS
Advanced NSCLCTargeted Therapies

REZILIENT 3: zipalertinib plus chemotherapy adds six months of first-line PFS

Sep 14 2026
CONGRESS
Advanced NSCLCTargeted Therapies

ARROS-1: first-line zidesamtinib responds in over 90% of ROS1-positive NSCLC

Giannis Mountzios
Sep 13 2026
CONGRESS
Advanced NSCLCADCsImmunotherapies

EVOKE-03: sacituzumab govitecan plus pembrolizumab misses both primary endpoints

G. Mountzios
Sep 13 2026
CONGRESS
Advanced NSCLCSCLCADCs

WCLC 2026, day 2: MRI surveillance without prophylactic cranial irradiation, and two relapse trials at 13.3 and 18.5 months

Sep 12 2026
CONGRESS
Advanced NSCLCResectable NSCLCSCLC

WCLC 2026, day 1: extended-interval and subcutaneous dosing in SCLC, and a 70% early response

Sep 09 2026
INDUSTRY NEWS
Advanced NSCLCImmunotherapies

HARMONi primary analysis reports 6.8 against 4.4 months PFS for ivonescimab plus chemotherapy after EGFR TKI progression

Sep 08 2026
RESEARCH
Advanced NSCLCImmunotherapies

Pleural metastases carried worse two-year survival than contralateral lung metastases in stage M1a NSCLC

L. Hendriks
Sep 04 2026
RESEARCH
Advanced NSCLCTargeted Therapies

An EGFR-SHC1 fusion resists EGFR inhibitors through its non-kinase partner

X. Le
Sep 03 2026
INDUSTRY NEWS
Advanced NSCLCImmunotherapies

Akeso reports an OS benefit for ivonescimab over pembrolizumab in PD-L1-positive NSCLC

Sep 02 2026
RESEARCH
Advanced NSCLCImmunotherapies

AI-HOPE registry recruits 920 patients to build machine-learning models for metastatic NSCLC outcomes

R. FerraraL. Hendriks
Aug 29 2026
RESEARCH
Advanced NSCLCADCs

International panel sets 55 consensus recommendations for managing Dato-DXd side effects in NSCLC

S. Saw
Aug 27 2026
RESEARCH
Advanced NSCLCADCsImmunotherapies

Two EORTC questionnaires cover the common side effects in NSCLC labels, and miss 62 rarer ones

J. RemonR. Ferrara
Aug 25 2026
RESEARCH
Advanced NSCLCBiomarkersImmunotherapies

Cleared ctDNA within weeks predicted longer survival on immunotherapy in a 109-patient study

P. Forde
Aug 21 2026
RESEARCH
Advanced NSCLCBiomarkersImmunotherapies

A ctDNA tumour fraction of 5 percent or more marks the patients who benefit from adding chemotherapy to checkpoint blockade

D. Planchard
Charles Rudin
Aug 09 2026
RESEARCH
Advanced NSCLCImmunotherapies

Radiation plus durvalumab without chemotherapy cleared its survival target in frail LA-NSCLC patients

C. Rudin
Aug 08 2026
RESEARCH
Advanced NSCLCBiomarkersTargeted Therapies

EGFR amplification at baseline marks shorter time on first-line osimertinib, in exon 19 deletions but not L858R

B. Ricciuti
Giannis Mountzios
Aug 07 2026
RESEARCH
Advanced NSCLCBiomarkersADCs

EVOKE-01 biomarker analysis: Trop-2 staining did not pick out who does better on sacituzumab govitecan than docetaxel

G. Mountzios
Aug 06 2026
RESEARCH
Advanced NSCLCTargeted Therapies

ORCHARD final data: osimertinib plus gefitinib gives modest benefit in EGFR C797X, and the authors advise against further study

X. LeZ. Piotrowska
Solange Peters
Aug 05 2026
RESEARCH
Advanced NSCLCImmunotherapies

AdvanTIG-301 closed early with 63 patients, leaving its stage III NSCLC comparisons descriptive

S. Peters
Aug 04 2026
RESEARCH
Advanced NSCLCTargeted Therapies

L858R with a TP53 co-mutation halved real-world PFS on front-line osimertinib

H. Borghaei
Jul 23 2026
INDUSTRY NEWS
Advanced NSCLCTargeted Therapies

Zidesamtinib approved in the US for previously treated ROS1-positive NSCLC

Jul 20 2026
INDUSTRY NEWS
Advanced NSCLCADCs

Sac-TMT plus pembrolizumab improves PFS in PD-L1-negative NSCLC

Jul 15 2026
RESEARCH
Advanced NSCLCImmunotherapies

Proton pump inhibitors and antibiotics linked to reduced durvalumab benefit in unresectable stage III NSCLC

A. CortelliniD. PlanchardJ. NaidooJ. RemonB. Ricciuti
Jul 14 2026
RESEARCH
Advanced NSCLCADCs

Trastuzumab deruxtecan in HER2-mutant NSCLC: evidence from the largest real-world cohort to date

M. HochmairG. MountziosA. AddeoM. Reck
Jul 14 2026
RESEARCH
Advanced NSCLCSCLCADCs

ADCs across solid tumours: an ETOP/IBCSG expert group sets the research priorities

R. StahelS. PetersG. MountziosA. PassaroN. ReguartJ. Remon
Jul 13 2026
INDUSTRY NEWS
Advanced NSCLCTargeted Therapies

Roche Reports Positive Phase 3 Results for Divarasib in Previously Treated KRAS G12C NSCLC